Ixabepilone is a semi synthetic analogue of ebomycin lactam. It is the first ebomycin class antitumor drug in the world. Compared with paclitaxel, the two drugs have different structures, but the mechanism of action is similar. Both drugs can induce tumor cell apoptosis by interfering with the division of cancer cells. The original research enterprise of isapiron is Bristol Myers Squibb, which was approved by FDA in October 2007. It is used to treat anthracyclines, taxane derivatives and capecitabine alone or in combination with capecitabine in the treatment of metastatic or locally advanced breast cancer.
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